Divalproex sodium

Divalproex sodium is sometimes used together with other seizure medications. If you are taking divalproex sodium only to prevent migraine headaches, this medication must not be used during pregnancy. This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Divalproex Sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities.

Divalproex dissociates to the valproate ion in the gastrointestinal tract.

A: Depakote ( divalproex sodium ) is used for the treatment of bipolar disorder, epilepsy (seizure disorder), chronic pain associated with neuropathy (damage to the nerves of the nervous system), and migraine headaches. The most common side effects with Depakote include nausea, vomiting,. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking divalproex sodiuMore common. Valproate, and its valproic acid , sodium valproate , and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.

They are useful for the prevention of seizures in those with absence seizures, partial seizures, and generalized seizures. They can be given intravenously or by mouth. Long and short acting formulations of tablets exist.

Common side effects include nausea, vomiting, sleepiness, and dry mouth. Is divalproex an antipsychotic? What are the side effects of divalproex? WARNINGS: Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first months of starting treatment.

Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first months, to monitor this side effect. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Experts are not exactly sure how divalproex sodium works although they suspect its activity is related. The benefits of therapy should be weighed against the risks. The incidence of fatal hepatotoxicity decreases considerably in progressively older patient groups.

Divalproex belongs to a group of drugs called anticonvulsants or anti-epileptic drugs. Available to patients with commercial prescription insurance coverage who meet eligibility criteria. A manic episode is a distinct period of abnormally and persistently elevate expansive, or irritable mood. Depakote (DEH-pah-kote) is a brand name used in the United States for a type of medicine called divalproex (di-VAL-pro-eks) sodium. The same product is known as Epival in Canada.

It is not available in every country. The active ingredient in Depakote changes in the body to valproate (val-PRO-ate),. Chemically it is designated as sodium hydrogen bis(2-propylpentanoate).

Figure 2: Mean plasma valproic acid concentration over time. Note in graphic Divalproex ER is the same as Divalproex SA in the text. Patients should be converted with an increase in dose of 8- when going to the SA product.

Valproate products include: valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, and Depakote ER), valproic acid (Depakene and Stavzor), and their generics. To convert from valproic acid to divalproex sodium , initiate divalproex sodium at same total daily dose and dosing schedule as valproic acid. Once patient is stabi- lizedondivalproexsodium,attemptadministration2–3timesdaily.

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