Lamotrigine unipolar depression

Is Lamictal a good medication for depression? Does Lamictal make you more depressed? How effective is Lamictal for bipolar II disorder? What treatment is used for unipolar depression?

However, many clinicians also use it in patients with a ( unipolar ) depressive disorder who have not responded adequately to conventional antidepressants.

I worked up to 75mg and stuck with that for several months. Circumstance lead to worsening depression and went to 150mg once daily and now at 200mg and holding steady. I have stopped years of benzo, Ativan, Klonopin, Xanax. Now only take Lamictal.

Lamotrigine is the only mood stabilizer that calms mood swings by lifting the depression rather than suppressing the mania, says Dr. That makes it a great choice for the bipolar spectrum, where the depressive symptoms usually outweigh the manic ones. To review the available data behind the use of lamotrigine in unipolar depression and common comorbid conditions.

A PubMed based literature review was conducted using keywords related to lamotrigine, depression , anxiety, post traumatic stress disorder (PTSD), obsessive–compulsive disorder (OCD), and personality disorders.

A large number of trials using lamotrigine for unipolar depression and. Consider lamotrigine as an adjunct for treatment-resistant major depression. It is useful for treating aggression and agitation in patients with traumatic brain injury or dementia. Borderline personality disorder patients treated with lamotrigine may show less affective lability, impulsivity, or aggression.

Dosing and Side Effects. The typical dose of lamotrigine is 1to 2milligrams per day, according to psycom. Various studies regularly reported partial rather than full response for lamotrigine in bipolar depression , both acute and maintenance. For depressive symptoms lamotrigine can serve as first choice drug for augmentation to a primary mood stabilizer for depressive symptoms.

The document has moved here. User Reviews for Lamotrigine to treat Depression (Page 2) Also known as: Lamictal, Lamictal XR, Subvenite, Lamictal ODT, Lamictal CD The following information is NOT intended to endorse drugs or recommend therapy. Furthermore, no information to recommend its use in other psychiatric disorders was found.

Lamotrigine augmentation may serve as a possible choice for patients with treatment-resistant unipolar depression and further trials are warranted to clarify the optimal dosage of lamotrigine augmentation together with the treatment duration and safety over time. Unipolar major depression – Unipolar major depression (major depressive disorder) is diagnosed in patients who have suffered at least one major depressive episode and have no history of mania or hypomania. A major depressive episode is a period lasting at least two weeks, with five or more of the following symptoms: depressed moo anhedonia.

A small number of retrospective studies and open label studies provided preliminary evidence for lamotrigine as an augmentation therapy in adults with treatment-resistant depression. There was little evidence to guide the use of lamotrigine for depression that had not responded to a course of anti-depressants.

Lamotrigine may be an effective treatment for depression , although have been inconsistent. In this exploratory pilot study we analyzed data from a five-month, uncontrolle open-label trial to determine if participants scoring higher on a measure of pretreatment irritability were more responsive to lamotrigine. Nineteen adults with unipolar or bipolar II depression completed five. A significant number of patients with unipolar depression fail to achieve remission after one or a series of antidepressants.

We present the of a retrospective chart review of the efficacy and tolerability of lamotrigine as an augmentation drug in treatment-resistant unipolar depression. It is unknown exactly how Lamictal helps with depression when not accompanied by mania. This type of unipolar depression is traditionally treated with serotonin reuptake inhibitors (SRIs).