Divalproex-EC ), which in a delayed-release pharmacokinetic profile and requires multiple daily doses. This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder ), and to prevent migraine headaches. It works by restoring the balance of certain.
Read more about the prescription drug DIVALPROEX SODIUM ENTERIC-COATED TABLET - ORAL. It is used to manage and control of certain types of seizures.
It can be used alone or in combination with other seizure control medications. Divalproex belongs to the family of medications called anticonvulsants. Enteric coated ( EC ) divalproaex pills are delayed release (DR). It also comes in a capsule filled with enteric coated pellets that can be swallowed or opened and sprinkled on soft food.
The tablets are approved for the treatment of seizures,. This medication is long acting and is referred to as “extended release” because the contents are released over an extended period of time,. This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Since the bioavailability of divalproex ER relative to divalproex was approximately 0.
AUC while switching a patient from divalproex to divalproex ER,. Depakote tablets are for oral administration. Alternatively, the capsule contents may be sprinkled on a small amount (roughly ml) of semisolid food (e.g., applesauce, pudding) immediately before swallowing.
Do not chew the sprinkle and food mixture. This drug is slightly less popular than other comparable drugs. Your condition may become worse if the drug is suddenly stopped. It is available in brand and generic versions.
Your dose may need to be gradually decreased. Take other medications as directed by your doctor for acute attacks. Inform your doctor if your condition does not improve. Accidental Release Measures Contain spill and collect, as appropriate. Transfer to a chemical waste container for disposal in accordance with local regulations.
Methods and Material For Containment and Cleaning Up: Avoid raising and breathing dust, and provide adequate ventilation. In women of childbearing potential unless the conditions of the pregnancy prevention programme are fulfilled (see sections and ). Half-life: to hours (average = hours). Conversion to once daily dosing: Consider only after a divided dose regimen on extended phenytoin capsules is established.
ER form produces lower blood levels. IV adminis-trationincompletebioavailability. Distribution: Rapidly distributed into plasma and extracellular water. Cross blood-brainbarrierandplacenta;entersbreastmilk.
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