Sedating antidepressants

Which antidepressant has the least side effects? Do SSRI antidepressants or 5-HTP work better? What are the best antidepressants? How to taper off your antidepressant?

At the low dose typically prescribed for sleep (mg), its blockade of histamine, serotonin, and alpha-receptors likely gives this drug its sedative effects. Side effects of antidepressants vary from one medication to another and from person to person.

Bothersome side effects, such as dry mouth, weight gain or sexual side effects,. Mild initial sedation is dose-dependent. May be least stimulating SSRI. Negligible drug-drug interactions. Tends to produce more initial nervousness and arousal than other SSRIs.

Very long half-life (7-days), so less likely to cause withdrawal on abrupt discontinuation. Sedative Withdrawal (drugs) Alternative treatments for Sedation. Antidepressants and Sedatives Depression.

The following products are considered to be alternative treatments or natural remedies for Sedation.

Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. An antidepressant should reverse abnormalities in the sleep pattern. However, many antidepressants can worsen sleep.

Because of the activating effects of some drugs, for example imipramine , desipramine , fluoxetine , paroxetine , venlafaxine , reboxetine and bupropion , many patients who take them have to be co-prescribed with sleep-promoting agents to improve sleep. Escitalopram has a rapid onset of antidepressant effect and is a good choice when rapid antidepressant response is desirable. Fluoxetine has the slowest onset of antidepressant action.

The most sedative SSRI Fluvoxamine and paroxetine are the most sedating of the SSRIs. Side effects: Sedation , fatigue, dry mouth, constipation, increased appetite, weight gain. I have problems with panic attacks and have tried Buspar and Effexor. I asked my doctor which of the newer antidepressants was the most sedating.

She stated that among the older ones (tricyclics), Imipramine, was the best for sedation. Overall, the risk of birth defects and other problems for babies of mothers who take antidepressants during pregnancy is low. Still, certain antidepressants , such as paroxetine (Paxil, Pexeva),. To achieve a therapeutic result, tea should be drunk for 2-months. The onset of antidepressant action of tea is possible not earlier than in 3-weeks.

Recipe 3: Powder of St. John’s wort from insomnia. Quite often depressive conditions are accompanied by sleep disturbances.

Doug, Remeron and Serzone would appear to be the most sedating new antidepressants available.

It is now believed that 5HTreceptor stimulation is subjacent to insomnia and changes in sleep organization related to the use of some antidepressants. CONCLUSION: Some drugs commonly prescribed for the treatment of depression may worsen insomnia and impair full recovery from depression. HTreceptor antagonists are promising drugs for treatment strategies since they can improve comorbid insomnia and depression. Ssri type antidepressants which are the most specific for the commonest biochemical defect in depression , low serotonin , are least likely amongst antidepressants to cause sedation, other than wellbutrin ( bupropion ) which rarely has sedative properties. It works as an SNRI, but affects norepinephrine to a greater extent than serotonin.

It is regarded as being safer in the event of overdose and less sedating than other tricyclic antidepressants. It is considered one of the first SSRIs and can also treat OC PTS and panic disorders. In general, all TCAs tend to be relatively sedating at first while the Hreceptor downregulates, but once it has fully desensitized (which it will, at least in my personal experience with mirtazapine), some TCAs like protriptyline and desipramine can indeed become quite activating.