Depakote pancreatitis

Why do steroids cause pancreatitis? What are the long term effects of pancreatitis? In a letter sent Monday to. Since those initial reports, similar case reports have followed. Outcomes for patients with valproic acid-associated pancreatitis have ranged from full recovery after discontinuation of the drug to severe acute pancreatitis and death.

Now there is a warning in the the literature on depakote that pancreatitis can be attributed to depakote.

HMG-COA REDUCTASE INHIBITORS. Case reports of druginduced AP have been published for all of the statins, with rosuvastatin the most recent statin implicated. If pancreatitis is diagnose valproate should ordinarily be discontinued. Nausea, hair loss, weight gain, and tremors also occur as less severe side effects.

Pancreatitis can develop at any. Pregnant women are also typically advised not to take the medication due to the risk of birth defects. Acute pancreatitis patients recover in majority of cases. Some may develop abscess, pseudocyst or duodenal obstruction.

These are required by the FDA and represent the most serious and possibly life-threatening risks of taking a medication.

Another potentially fatal side effect is inflammation of the pancreas, or pancreatitis. This is when digestive enzymes start digesting the pancreas itself. Phelps, Thank you so much for this web site. He is 15-years-old and is the typical adolescent with bi-polar. Depakote carries three black box warnings.

DEPAKOTE ER 2and 5mg tablets are for oral administration. Some patients have experienced liver damage, birth defects, pancreatitis and other side effects which resulted in serious injury or even death. Signs of pancreatitis include severe abdominal pain, nausea, vomiting and inability to keep food down. Drug‐induced pancreatitis constitutes ∼ of acute pancreatitis cases in children, and corticosteroids are the most common cause, accounting for ∼ of cases in one series 3. General Dosing Advice 2. Dosing in Patients Taking Rufinamide DOSAGE FORMS AND STRENGTHS CONTRAINDICATIONS WARNINGS AND PRECAUTIONS 5. Structural Birth Defects 5. Decreased IQ Following in utero Exposure 5. Use in Women of Childbearing Potential 5. Problem I had with depakote was that I developed pancreatitis (most likely from drinking) but since they could not rule out the depakote they had to take me off of it. Cases of life-threatening pancreatitis have been re ported in both children and adults receiving valproate.

Some of the cases have been described as hemorrhagic with a rapid progression from initial symptoms to death. Cases have been reported shortly after initial use as well as after several years of use.

An early case report and review of the literature helped clearly establish valproic acid as a cause of pancreatitis and warned about the need to consider pancreatitis in any patient presenting.